Falimint

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The active ingredient Falimint is an aromatic nitro compound.

The effect of the drug is similar to the effect of menthol:

• there is a feeling of pleasant coolness in the mouth and throat;
• no dryness or numbness occurs;
• breathing becomes easier immediately;
• reflex cough stops;
• mucus thins;
• pain is alleviated;
• the inflammatory process decreases;
• if there was a urge to vomit during medical manipulations in the oral cavity, they are suppressed.

Pharmacokinetics

After oral administration, Falimint is quickly absorbed. The maximum concentration of unchanged drug in plasma is achieved after 30-60 minutes.

It is excreted from the body in the form of metabolites in the urine. The maximum concentration of the altered drug in the urine is observed 2 hours after taking the tablets.

Directions for use and dosage

The manufacturer's instructions for the drug indicate a maximum duration of use of 5 days
. Exceeding the recommended duration is fraught with consequences. The patient may show signs of an allergy to the components of the drug, and addiction will form.

The necessary therapeutic effect will be completely absent with subsequent uses of the drug Falimint. There are peculiarities when using dragees. To achieve a therapeutic effect, you should not consume food or liquid of any kind during resorption and immediately after it.

For adults

The maximum permissible daily intake for an adult is 250 mg. It corresponds to 10 tablets. During one dose, the patient can dissolve 1-2 tablets. It is permissible to repeat the procedure 3-5 times throughout the day. The dragee is not chewed or swallowed; it is held behind the cheek or under the tongue, waiting for gradual dissolution.

For children

Due to the lack of medical observations about the effect of the drug on children under 5 years of age, Falimint tablets are prescribed to school-age children. The daily dose for a child is 75 mg. It corresponds to 3 tablets. Children should dissolve 1 tablet 3 times a day.

During pregnancy and breastfeeding

Cough and sore throat are common during pregnancy. The immune system of expectant mothers is weakened. Self-medication during this period is especially dangerous. The expectant mother is responsible for the health of the unborn child.

Indications for use

What Falimint tablets help with:

• diseases of the respiratory system, in which a pronounced inflammatory process is observed, in particular, tablets are taken for pharyngitis , laryngitis and tonsillitis ;
• inflammatory processes in the oral cavity, for example, stomatitis or gingivitis ;
• non-productive, dry reflex cough ;
• pronounced gag reflex during medical manipulations in the mouth and pharynx.

In most cases, in the treatment of inflammatory diseases it is used as an adjuvant.

Application Guide

The dosage is prescribed only by the attending physician according to the indications and the form of the disease. Falimint should be dissolved slowly in the mouth, without drinking water. Doctors prescribe his appointment:

• if there is a painful sensation in the throat that makes it difficult to swallow, redness;
• there is a characteristic dry cough without sputum production;
• with tension in the vocal cords;
• a sore throat provokes a debilitating cough;
• the respiratory organs became inflamed.

The product helps well with sore throat due to the fact that it has the effect of local anesthesia and soothes the tonsils. It has an effect on the infected throat area and can relieve pain. With properly selected complex treatment, its use is advisable for diseases of the tonsils.

When using the drug, precautions must be taken. You should not take it for a long time due to the possible occurrence of an allergic reaction.

It is recommended to replace Falimint with other medications. It is not advisable to eat or drink immediately after taking the pills. The duration of use should not exceed more than seven days.

The doctor does not prescribe this drug to a child, since its effect on a growing young body has not been fully studied, and how it interacts with other medications is still unknown.

Instructions for use of Falimint (Method and dosage)

The tablets should dissolve in the mouth. Take one tablet, no more than 10 tablets per day.

The medicine can only be used for a few days. The duration of the course is individual and should be selected by the attending physician. But if during this time the disease has not gone away, there is no need to extend the course, it is better to choose another drug.

Instructions for the use of Falimint for children have not been developed, since there is not enough information regarding the effectiveness and safety of using the medicine to treat children.

Why was Falimint discontinued?

This response from the Russian representative office did not completely clarify the situation, but it became clear that there was no point in waiting for the drug to return to the market. However, new questions arose: for what reason was production discontinued and did Falimint pose a health threat? It is difficult to reliably answer the first one, but it is possible to analyze in detail the main characteristics of the drug.

Pharmacological action and indications

When using Falimint tablets, it eliminates dry, unproductive cough and has a mild analgesic effect. When absorbed, a feeling of coolness occurs in the mouth, while the mucous membranes do not dry out. This effect alleviates the condition of the following diseases of the oral cavity and pharynx:

• pharyngitis;
• laryngitis;
• stomatitis;
• tonsillitis;
• gingivitis.

The drug is also indicated as a prophylaxis before dental procedures and instrumental examinations.

Components of the drug

In addition to the main active ingredient - the antiseptic acetylaminonitropropoxybenzene (25 mg for each pill) - Falimint contains numerous auxiliary ingredients. These include sucrose, paraffin, copovidone, talc, glucose syrup and others. All of them are safe and do not pose a threat to the health of patients. There are no publications on the identified toxicity of acetylaminonitropropoxybenzene, so the composition of the pill cannot be a basis for a ban.

Side effects and contraindications

In this list, the manufacturer included only individual intolerance to the ingredients of the drug, since no other manifestations of negative effects on the body were noted. However, the instructions indicate that the use of Falimint by pregnant and lactating women is not recommended. This limitation is due to the fact that clinical trials of the drug have not been conducted. For the same reason, there is no data on the interaction of drugs with other drugs.

Clinical and post-marketing studies

The lack of RCTs (randomized clinical trials) is a serious drawback for any drug. However, during post-marketing observations, no negative reviews indicating toxicity were received. Patients generally assessed the effectiveness of the drug positively; life- and health-threatening situations did not arise after taking the pills.

Thus, the most likely reason for the termination of the production of Falimint is non-compliance with the requirements for the production process or complaints about the quality of raw materials from regulatory organizations.

special instructions

When treating with Falimint, you should adhere to the following recommendations:

• it is necessary to stop taking the medication if signs of a skin allergic reaction appear;
• patients with diabetes should remember that the medicine contains a certain amount of sugar (1 tablet – 0.03 bread units);
• Tablets should not be taken by persons with congenital intolerance to glucose or fructose, with glucose-galactose malabsorption or sucrose-isomaltose deficiency;
• You should not take the medicine for more than a few days.

Analogs

Matches by level 4 ATC code:
Suprima-ENT

Ingalipt-N

Strepsils Plus

Strepsils

Ingalipt

TheraFlu LAR

Hexoral Tabs

Lisak

Efizol

Angilex

Kameton

Anzibel

Agisept

Yox

Lugol's solution with glycerin

Lugol

Laripront

Stopangin 2A

Stopangin

Septolete Neo

Analogues of Falimint:

• Agisept;
• Vocasept;
• Hexoral Lorcept;
• Gorpils;
• Gripcold;
• Koldakt Lor Pils;
• Rinza Lorsept;
• Strepsils;
• Suprima-Lor;
• Trisils.

Falimint's analogs

The withdrawal of a drug from production in Russia is an unpleasant event for adherents of the drug. However, this fact should not cause disappointment, especially since you can find a wide variety of effective analogues in the pharmacy chain. All substitute drugs have a different structure, but have a similar therapeutic effect. They can have a simple or complex composition.

Table - Analogues of Falimint

Most analogues have a more affordable price and allow you to reduce the financial costs of treatment.