Skin damage and wounds are always unpleasant. What can we say about trophic ulcers - companions of severe varicose veins, which are characterized by very sluggish and slow healing due to impaired tissue nutrition. Solcoseryl can help heal such difficult lesions, as well as burns, frostbite, and eye damage.
- Solcoseryl ointment as a face cream
- How to use Solcoseryl and Dimexide for wrinkles
In what forms is the drug available?
The manufacturer produces Solcoseryl in the form of ointment and gel for external use, as well as ophthalmic gel. In addition, this drug is available in injection form.
The active substance in all cases is calf blood extract - hemoderivat. Auxiliary components for each of the release forms are individual. Thus, in addition to the active substance, the solution contains only water for injection, and, for example, the manufacturer adds a number of ingredients to the ointment: white petrolatum, methyl parahydroxybenzoate, cetyl alcohol, etc.
The uniqueness of the composition of solcoseryl
The ointment has a uniform, greasy texture; the color can vary from deep white to yellow, with a characteristic odor of broth and petroleum jelly.
The active components of solcoseryl include deproteinized (removal of proteins) hemoderivat from the blood of 3-month-old calves at a concentration of 2.07 mg/g. Auxiliary components are represented by methyl parahydroxybenzoate and propyl parahydroxybenzoate (preservatives), palmitic alcohol (emulsifier), white petrolatum (ointment base), water for injection (dissolution of dry dialysate).
An analogue of the drug is Actovegin ointment. These drugs appeared on the pharmaceutical market almost simultaneously and differ only in the manufacturer and price.
The main active ingredient of solcoseryl is a deproteinized hemoderivat, which is obtained by dialysis and subsequent ultrafiltration. During the production process, high molecular weight proteins are removed (deproteinization). This is a complex compound that includes natural low-molecular substances with a molecular weight of up to 5000 Da.
Such a unique composition cannot be reproduced in laboratory conditions. Basically, these are electrolytes, amino acids, nucleotides, nucleosides. The effectiveness of only some of these substances has been described and proven from a pharmacological point of view. However, in vitro tests have proven the effectiveness of solcoseryl in the treatment of damaged tissues and wound surfaces.
What kind of medicine is Solcoseryl?
The drug has a beneficial effect on tissue metabolic processes. It improves tissue nutrition in case of damage, and also activates repair and regeneration processes.
Solcoseryl in injection form is used for extensive circulatory disorders (diseases of peripheral veins and arteries, strokes), ointment and jelly are used to treat ulcerative lesions and slow-healing wounds, and the gel is an ophthalmic agent. Thus, each of the release forms performs its own task of restoring damaged tissue.
The rate of absorption and distribution of the drug in the body, as well as the route of its elimination, cannot be determined by methods usual in pharmacology due to the characteristics of the active substance.
According to the results of a study of the drug on animals, the pharmacological effect develops within half an hour after the bolus injection. The therapeutic effect lasts for 3 hours.
Indications
For each release form of Solcoseryl there are individual indications.
In the form of injections, the drug is prescribed when a patient is diagnosed with:
- occlusive peripheral artery disease grade 3 or 4;
- disturbances of venous blood flow with trophic lesions;
- strokes and traumatic brain injuries, which led to disruption of metabolic processes in the brain.
Ointment and gel for external use are used in complex treatment:
- minor abrasions and wounds;
- mild to moderate burns, frostbite;
- difficult-to-heal skin lesions: trophic ulcers, bedsores.
Ophthalmologists recommend the use of Solcoseryl eye gel to patients for the treatment of:
- injuries of the cornea and conjunctiva, their erosive lesions;
- scars after ophthalmological operations;
- eye burns of various types;
- dystrophic lesions of the cornea.
In addition, this gel is indicated for use in case of discomfort when wearing contact lenses and to reduce the time of getting used to them.
Solcoseryl (gel), 1 pc., 20 g, gel for external use
Solcoseryl injection solution:
IV
or
IM
.
In the treatment of occlusive diseases of peripheral arteries in stages III–IV according to Fontaine
- IV 20 ml daily. Intravenous drip administration in isotonic sodium chloride solution or 5% glucose solution is possible. The duration of therapy is up to 4 weeks and is determined by the clinical picture of the disease.
In the treatment of chronic venous insufficiency accompanied by trophic disorders (Ulcera cruris)
- IV 10 ml 3 times a week. The duration of therapy is no more than 4 weeks and is determined by the clinical picture of the disease. An important additional measure aimed at preventing peripheral “venous” edema is the application of a pressure bandage using an elastic bandage.
In the presence of local trophic tissue disorders, simultaneous therapy with Solcoseryl jelly and then Solcoseryl ointment is recommended.
In the treatment of ischemic and hemorrhagic strokes in severe and extremely severe forms
as the main course - 10 or 20 ml intravenously, respectively, daily for 10 days. Upon completion of the main course - 2 ml intramuscularly or intravenously for 30 days.
Traumatic brain injury (severe brain contusion)
- IV 1000 mg, daily for 5 days.
If intravenous administration of the drug is not possible, the drug can be administered intramuscularly, usually 2 ml per day undiluted.
When using the undiluted drug intravenously, it must be administered slowly, since it is a hypertonic solution.
Solcoseryl gel, ointment:
topically.
Apply directly to the wound surface after preliminary cleansing of the wound using a disinfectant solution.
Before starting treatment of trophic ulcers, as well as in cases of purulent infection of the wound, preliminary surgical treatment is necessary.
Solcoseryl gel is applied to fresh wounds, wounds with wet discharge, and to ulcers with signs of weeping - a thin layer on a cleaned wound 2-3 times a day. It is recommended to lubricate areas where epithelization has begun with Solcoseryl ointment. The use of Solcoseryl gel continues until pronounced granulation tissue forms on the damaged skin surface and the wound dries out.
Solcoseryl ointment is used primarily for the treatment of dry (non-wetting) wounds.
Solcoseryl ointment is applied in a thin layer to a cleaned wound 1-2 times a day; it can be used under bandages. The course of treatment with Solcoseryl ointment continues until the wound is completely healed, its epithelization and the formation of elastic scar tissue.
For the treatment of severe trophic damage to the skin and soft tissues, the simultaneous use of parenteral forms of Solcoseryl is recommended.
Side effects
The use of an injection solution in rare cases can lead to the development of allergic reactions, including anaphylactic shock. In this situation, you should immediately stop using the drug and prescribe symptomatic therapy in the form of antihistamines.
In addition, the process of performing the injection itself can be painful for the patient due to the potassium it contains.
When using the ointment, some patients may experience a burning sensation at the site of application.
Solcoseryl eye gel may cause short-term irritation, which is not an indication to discontinue treatment. The development of allergic reactions when using external forms of the drug is extremely rare.
Possible side effects and contraindications
Very rarely, urticaria, itching, redness, and marginal dermatitis appear at the site of application of solcoseryl. If such allergic reactions occur, it is recommended to stop using the ointment and consult a doctor to change the drug.
Solcoseryl is contraindicated in case of hypersensitivity to the components of the ointment. It is also recommended to use it with caution in patients prone to allergies.
Solcoseryl in cosmetology: effective fight against wrinkles
Women appreciated the effect of the drug on the condition of the skin, although the instructions do not contain instructions for using solcoseryl for the face. Based on it, recipes for many masks have been created that effectively even out skin tone, promote the healing of microtraumas, and solcoseryl also helps get rid of wrinkles.
Cosmetologists explain the effectiveness of solcoseryl as a cosmetic product by the pharmacological action of the drug. Stimulating metabolism in cells, collagen synthesis and activating tissue repair make it possible to use solcoseryl to combat wrinkles.
However, there are no studies that would confirm its effectiveness, which does not prevent the drug from being used in beauty salons and at home as part of a variety of face masks. Women consider the safety and low cost of procedures to be the indisputable advantage of cosmetics with the addition of solcoseryl.
Cosmetologists claim that solcoseryl ointment moisturizes and nourishes the skin, promotes the healing of small cracks and saturates cells with oxygen. The ointment is mixed with nourishing cream in a 1:1 ratio and the mixture is applied to the facial skin twice a week at night. Solcoseryl can be used undiluted as a face mask. The ointment is applied to the skin for 1.5 hours, after which it is washed off with warm water.
The ointment is especially effective as a lip balm. To do this, solcoseryl is mixed with your favorite balm and applied to the skin of the lips. This product helps to quickly restore damaged skin.
Mode of application
Solution
Solcoseryl in the form of a solution is recommended to be administered intravenously slowly in the form of an injection or by drip, having previously diluted it with saline solution or 5% glucose solution. If intravenous administration is difficult, intramuscular injection is allowed.
For the treatment of venous insufficiency, the drug is prescribed for up to a month, combining it with the application of an external gel or ointment to the area of trophic ulcers.
Patients who have suffered a stroke are prescribed a course of treatment with Solcoseryl for 5 weeks. When treating traumatic brain injuries, short courses lasting 5 days are prescribed.
Ointment and gel
Ointment and gel for external use are applied directly to the wound. Before using them, the wound surface is thoroughly disinfected. In the presence of purulent discharge, surgical treatment may be required.
The gel is used to treat wet, fresh wound surfaces. When the affected area begins to epithelialize, granulation tissue appears and the wound dries out, you should switch to using Solcoseryl in the form of an ointment.
The course of treatment with external forms of the drug is carried out until the wound surface is completely healed and a scar is formed.
Ophthalmic gel
The eye gel is instilled into the conjunctival cavity 3-4 times a day, one drop at a time. In some cases, it is possible to use the drug hourly. The course of treatment lasts until complete recovery.
Pharmacological action of the ointment
The pharmacological properties of the drug have not been fully studied. However, during the studies it was proven that solcoseryl has the following properties:
- in case of oxygen deficiency, its delivery to damaged cells is ensured;
- glucose transfer in metabolic disorders;
- is a catalyst for the formation of intracellular ATP;
- ensures the storage of energy in mitochondria generated during the transformation of nutrients;
- supports cells during nutritional deficiencies by supplying high-energy phosphates;
- prevents or prevents atypical changes with minor cell damage;
- “launches” the process of natural restoration of cells and tissues;
- activates the proliferation (division and formation) of fibroblasts that form the framework of connective fibers, and the formation of collagen filaments in the walls of blood vessels.
The ointment is widely used in cosmetology, gynecology, ophthalmology, and dentistry.
Main indications for use of the product
Ointment with solcoseryl is recommended for:
- minor skin damage in the form of abrasions;
- burns (except chemical) 1-2nd degree, which occur without the formation of exudate;
- frostbite of the 1st-2nd degree in the absence of wound weeping;
- psoriasis;
- to eliminate dry calluses and corns;
- to prevent the formation of scars after laser removal of warts or moles;
- atopic and seborrheic dermatitis;
- “sticking” in the corners of the mouth;
- drying of the nasal mucosa;
- in the treatment of wounds that heal poorly, including trophic ulcers and bedsores, after removal of dead tissue.
As a rule, a gel with solcoseryl is first applied to treat the wound surface with the separation of exudate. After the first signs of wound granulation appear, therapy is continued with the drug in the form of an ointment.
Differences between the ointment form of solcoseryl and the gel form
Pharmacies offer 2 forms of the drug intended for external local use. How do they differ and is it necessary to pay attention to such nuances?
The main differences between the forms are due to the excipients. Thus, solcoseryl gel does not contain fatty bases, which is why it is quickly washed off with warm water and removed from the surface of the skin. Due to this, it is the gel form that stimulates the formation of granulation tissue and the elimination of wound exudate.
When the wound dries out and signs of granulation appear, it would be more appropriate to use ointment. The fatty base of the drug forms a protective film on the surface of the wound, so the healing process is noticeably faster. In addition, solcoseryl ointment softens the surface of the wound, thereby avoiding the appearance of scars and other skin defects.
